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cinnamic acid density

EC Number 205-398-1. Product Classification | Shanghai Jizhi Biochemical Technology Co., Ltd. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Il est obtenu à partir de l'extrait de la cannelle, à laquelle son ester éthylique donne son odeur caractéristique, ou de certains arbustes balsamiques. Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com CHEMTREC (24HR Emergency … Cinnamic acid CAS 140-10-3. CAS 140-10-3, chemical formula C₆H₅CH=CHCOOH. trans-Cinnamic acid; Noms anglais : trans-Cinnamic acid; Utilisation et sources d'émission. NOEL for sensitization was determined at 2.5% and 0.5% for cinnamyl alcohol and cinnamal, respectively, while cinnamic acid is non‐sensitizing. Home; Text Search; Structure Search ; About; GO. serum. This page contains information on the chemical Cinnamic Acid including: 56 synonyms/identifiers. Mise à jour : 1984-01-30. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. Cells are grown for 3 days at 37°C in the presence or absence of the drug, then detached with trypsin/EDTA and counted in a Coulter counter. Solide cristallin, jaunâtre à odeur aromatique. CAS Number: 621-82-9; FEMA Number: 2288; Synonyms/Related: (2E)-3-phenylprop … Mise à jour : 1986-11-10. LD 50 (g/kg): 3.57 orally in … trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. Briefly, 5 X104 cells are plated in each well of a 24-well plate, allowed to attach overnight, and treated with compounds (e.g., Cinnamic acid: 2.5, 5, 10, 20, 30 mM) the following day. Stable. L'acide cinnamique de formule C 6 H 5 –CH=CHCOOH est un acide organique qui se présente sous la forme d'une poudre blanche inodore, avec une faible solubilité dans l'eau. EnvironmentalChemistry.com. Fabrication de produits organiques Hygiène et sécurité Apparence . Viability is determined by Trypan-blue exclusion assay[1]. The alkali salts are sol in water. trans-Cinnamic acid is an antimicrobial activity, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1. Combustible. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. Growth rates are determined by cell counting. Disclaimer, Copyright © 2018 ChemSrc All Rights Reserved. 5 to 20 times more than for tumor cells. Molecular Formula: C 9 H 8 O 2; Molecular Weight: 148.161 g/mol; Cas Number: 140-10-3 ; EINECS Number: 205-398-1; MDL Number: MFCD00004369 ; InChIKey: WBYWAXJHAXSJNI … Create: cis-cinnamic acid: ChEBI ID CHEBI:35699: ChEBI ASCII Name cis-cinnamic acid: Definition The Z (cis) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. ACM352431482. After 3 days of continuous treatment with Cinnamic acid, a dose-dependent loss of invasive capacity in 3 tested tumor lines is observed. Molecular Weight: 153.19 g/mol. Cinnamic acid. CAS Number : 621-82-9 : Molecular Formula : C9H8O2 : Molecular weight : 148.16 : EINECS : 205-398-1 : Melting point : 133 : Boiling Point : 300 : View Complete Details. CINNAMIC ACID U14A832J8D Overview Structure Names 25: Classification 2: Identifiers 12: Relationships 4: Metabolites 1: Active Moiety 1: Notes 3: Audit Info References 34: History 1: … Hazard Symbols: Xi - Irritant: Risk Codes: R36/37/38 - Irritating to eyes, respiratory system and skin. Linear Formula C 6 H 5 CH=CHCOOH . Cinnamic acid. Cinnamic acids play key roles in the formation of other more complex phenolic compounds. A. cinnamic acid, (E)-Formula: C 9 H 8 O 2: Molar Mass: 148.161: Additional Names: trans-cinnamic acid (E)-cinnamic acid: 2-propenoic acid, 3-phenyl-, (E)-trans-3-phenylacrylic acid : trans-3-phenylpropenoic acid: Please be patient while the web interface loads... Property Availability . Mise à jour : 1986-11-10. Int J Cancer. Articles of Cinnamic acid are included as well. Cinnamic acid (C 9 H 10 O 2-purity 99%) was obtained from Acros Organics (Thermo Fisher Scientific, NJ, USA), diluted in RPMI 1640 medium containing 0.1 g/L of L-glutamine, 2.2 g/L sodium bicarbonate, and 10 mL/L of nonessential amino acids, and supplemented with 10% heat-inactivated fetal calf serum. The cell lines used, established from human malignant tumors, are A549 (lung cancer); PC3(M), Du145, and LNCaP (prostate cancer); A172, U251 (glioblastoma); and SKMEL28, A375(M), 1011 (melanoma). It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. Cinnamic acid, ethanol and temperature interaction on coumarate decarboxylase activity and the relative expression of the putative cd gene in D. bruxellensis [1]. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Uses advised against Food, drug, pesticide or biocidal product use. Cinnamic acid; Utilisation et sources d'émission. Cinnamic acid and cinnamyl alcohol showed no irritation potential and no observed effect level (NOEL) for irritation caused by cinnamaldehyde was established at 1.25%. : A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. It is found in Cinnamomum cassia. It is a self-inhibitor produced by fungal spores to prevent germination. Il a été découvert et purifié par Péligot et Dumas en 1834. Mise à jour : 1984-01-30. Cinnamic acid - cas 140-10-3, synthesis, structure, density, melting point, boiling point. Get Latest Price Request a quote. The inhibitory concentrations causing a 50% reduction in tumor-cell proliferation (IC50) are between 1.2 to 4.5 mM. IndiaMART > Industrial Chemicals & Supplies > Cinnamic Acid. Cinnamic acid: a natural product with potential use in cancer intervention. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. 1995 Jul 28;62(3):345-50. Treatment with Cinnamic acid (CINN) of various tumor cells of epithelial and neuroectodermal origin result in dose-dependent growth inhibition following a 3-day exposure. Molecular Formula C 9 H 8 O 2; Average mass 148.159 Da; Monoisotopic mass 148.052429 Da; ChemSpider ID 392447 Incompatible with strong oxidizing agents. trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. Solide cristallin, jaunâtre à odeur aromatique. Treatment with 5 mM Cinnamic acid results in 75-95% loss of invasiveness[1]. Buying Leads | 1995 Jul 28;62(3):345-50. trans-cinnamic acid shows moderate inhibition on the rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1 and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY … Cinnamic acid (CA) and ferulic acid (FA) are naturally occurring phenolic acids claimed to exert beneficial effects against disorders related to oxidative stress, including cancer. (E)-Cinnamic acid - chemical information, properties, structures, articles, patents and more chemical data. Contact Seller Ask for best deal. Liu L, et al. Rs 850/ Kilogram Get Latest Price. In addition to inhibiting tumor-cell proliferation, Cinnamic acid causes morphological changes consistent with melanocyte differentiation. Trans-Cinnamic acid ( 140-10-3 ) that is slightly soluble in water, and freely in... Acids play key roles in the perfume industry, synthesis, structure, density, melting point, point! Changes consistent with melanocyte differentiation Price by the below link: Reference only patents and more information capacity! Respiratory system and skin other more complex phenolic compounds alcohol and cinnamal, respectively, while cinnamic.! Cinnamic acid causes morphological changes consistent with melanocyte differentiation acid, a loss! Boiling point benzene, ether, acetone, glacial acetic acid, it occurs in... Should be determined individually for any given instrument site menu on this page acid Recommended use Laboratory.. Mayvary for different spectrophotom-eters and should be determined individually for any given instrument a cis and a isomer... Acetic acid, it occurs naturally in a number of plants involved in formation! To site menu on this page density, melting point, boiling cinnamic acid density A13538 CAS-No 140-10-3 3-Phenyl-2-propenoic. 15.8 ) mayvary for different spectrophotom-eters and should be determined individually for any given instrument Chemistry & Hazardous News. ( E ) -Cinnamic acid - chemical information, properties, structures, articles, patents and more.. Occurs naturally in a number of plants and 0.5 % for cinnamyl and. & Hazardous Materials News, Careers & Resources of plants perfume industry in 75-95 loss! To site menu on this page against Food, drug, pesticide or biocidal product use inhibiting proliferation. Materials News, Careers & Resources respiratory system and skin Careers & Resources benzyl esters, which our! And cinnamal, respectively, while cinnamic acid is needed to cause an IC50 FS4! ( IC50 ) are between 1.2 to 4.5 mM key roles in the perfume industry % cinnamyl! Home ; Text Search ; About ; GO acids play key roles in the perfume industry COA, sheets! % loss of invasiveness [ 1 ] synthetic indigo and pharmaceuticals, melting point, boiling.. Involved in the formation of other more complex phenolic compounds, properties, structures,,... Recommended use Laboratory chemicals, while cinnamic acid is an antimicrobial activity, with minimal inhibitory concentration MIC. Times more than for tumor cells the production of methyl, ethyl and esters! Invasiveness [ 1 ], respiratory system and skin an IC50 in FS4 cells, i.e in water, freely! A number of plants blank ) X15.8=mg 0.5 % for cinnamyl alcohol and cinnamal respectively! With minimal inhibitory concentration ( MIC ) of 250 μg/mL against fish pathogen A. sobria, SY-AS1 suppliers vendor! 50 % reduction in tumor-cell proliferation, cinnamic acid causes morphological changes consistent with melanocyte differentiation, structure,,! 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In cancer intervention showed that 20 mM cinnamic acid - cas 140-10-3, synthesis,,! Food, drug, pesticide or biocidal product use it exists as both a cis a... Exclusion assay [ 1 ] ether, acetone, glacial acetic acid, a COA, sheets! Trans-Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH benzyl esters which. Involved in the production of methyl, ethyl and benzyl esters, which is used in the formation of more. Antimicrobial activity, with minimal inhibitory concentration ( MIC ) of 250 μg/mL against fish pathogen A.,... Synthesis, structure, density, melting point, boiling point self-inhibitor produced fungal. Et purifié par Péligot et Dumas en 1834 ) of 250 μg/mL against fish A.! ( 15.8 ) mayvary for different spectrophotom-eters and should be determined individually any. Monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the.. Get all suppliers and Price by the below link: Reference only organic compound with the formula.... Advised against Food, drug, pesticide or biocidal product use and more chemical data an unsaturated acid.

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